High stereoselectivity in chelation-controlled intermolecular Heck reactions with aryl chlorides, vinyl chlorides and vinyl triflates.
نویسندگان
چکیده
Highly stereoselective chelation-controlled Pd(0)-catalyzed beta-arylations and beta-vinylations of a five-membered chiral, pyrrolidine-based vinyl ether were achieved using aryl- and vinyl chlorides as substrates, yielding quaternary 2-aryl/vinyl-2-methyl cyclopentanones in 89-96% ee under neutral reaction conditions.
منابع مشابه
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 6 4 شماره
صفحات -
تاریخ انتشار 2008